Can Microsporum canis be treated?
A variety of oral and topical antifungal agents is available and drugs such as griseofulvin (Gri), terbinafine (TER), itraconazole (IT), and fluconazole (FLZ) are used to cure severe infections in humans and animals [2,13,14].
What does Microsporum canis do to animals?
Microsporum canis is a pathogenic, asexual fungus in the phylum Ascomycota that infects the upper, dead layers of skin on domesticated cats, and occasionally dogs and humans.
What are the symptoms of Microsporum canis?
mentagrophytes, or Microsporum canis may be found in all ruminants and New World camelids in children’s zoos. Animals may be asymptomatic carriers or display clinical signs of the typical circular lesions of alopecia on the face and ears, with or without pruritis. Diagnosis is via Wood’s lamp, skin, and hair cultures.
How does Microsporum canis damage cells?
Similar to other fungal dermatophytes, M. canis also secretes keratinolytic protease and gains energy from keratin in nails, hair, and skin. This organism degrades keratin into easily assimilable metabolites that can be utilized as the nutrition and causes some damages to the skin and hair follicle.
What is Microconidia and macroconidia?
Relatively large and complex conidia are termed macroconidia while the smaller and more simple conidia are termed microconidia. The presence/absence of conidia and their size, shape and location are major features used in the laboratory to identify the species of fungus in clinical specimens.
What does Microsporum gypseum cause?
Dermatophytosis caused by M. gypseum usually manifests as an inflammatory mycosis that typically affects the glabrous skin and scalp, especially in children. Rarely, it can present as onychomycosis.
How is Microsporum gypseum spread?
Transmission occurs via direct contact with an infected animal or person, or by contact with infected hair and scale on fomites or in the environment.
How is Microsporum Gypseum spread?
What does Microsporum Gypseum cause?
Is Microsporum canis an ectothrix?
Microsporum canis scalp ringworm: its primary or secondary ectothrix character.
What is Tuberculate Macroconidia?
The tuberculate macroconidia are usually diagnostic; however, the presence of both macro- and microconidia are not required for diagnosis. Fungi belonging to the genus Sepedonium also form similar tuberculate macroconidia; however, they are not dimorphic and do not form microconidia (3).
What does the Microconidia do?
The microconidia can function either as spermatia (male gametes) or as asexual reproductive structures or both. In nature they probably function exclusively in fertilization of protoperithecia.
What is Microsporum canis in cats?
Microsporum canis. Microsporum canis is a pathogenic, asexual fungus in the phylum Ascomycota that infects the upper, dead layers of skin on domesticated cats, and occasionally dogs and humans. The species has a worldwide distribution.
Does Microsporum canis produce microconidia?
The interior portion of each macroconidium is typically divided into six or more compartments separated by broad cross-walls. Microsporum canis also produces microconidia that resemble those of many other dermatophytes and thus are not a useful diagnostic feature.
What are Microsporum hyphae and macroconidia?
Microsporum canis produces septate hyphae, macroconidia, and microconidia. Macroconidia are spindle-shaped, with an asymmetrical apical knob. They are 6- to 15-celled, long, rough and have thick outer cell walls. The septal walls are thin. Microconidia are rare, unicellular and clavate to pyriform in shape.
What are the characteristics of macroconidia in Mycoplasma Canis?
The macroconidia are fusiform, verrucose with thick and coarsely roughened cell walls. Each macroconidium is typically divided into six or more compartments separated by broad cross-walls. M. canis also produces a few pyriform to clavate microconidia.