Is synthetic B12 effective?
Cyanocobalamin is a synthetic form of vitamin B12 that’s not found in nature ( 2 ). It’s used more frequently in supplements, as it’s considered more stable and cost effective than other forms of vitamin B12.
How effective are B12 supplements?
Research now shows that high doses of oral vitamin B12 (eg. 1000mcg daily) can be just as effective at treating deficiency, even in the absence of intrinsic factor, and may be a suitable alternative to intramuscular injections for many people.
Do B12 tablets work as well as injections?
If you have vitamin B12 deficiency, vitamin B12 tablets may be as effective as injections. They are readily available, cheaper, and taken orally with ease. However, vitamin B12 injections are more readily absorbed in the body and do not have to be administered as often as oral tablets.
How long does it take to correct a vitamin B12 deficiency?
Once you begin treating your vitamin B12 deficiency, it can take up to six to 12 months to fully recover. It is also common to not experience any improvement during the first few months of treatment. If you can, it’s a good idea to address what’s causing the deficiency.
Can you have too much B12?
Since B12 is a water-soluble vitamin, it’s generally considered safe, even at high doses. No Tolerable Upper Intake Level (UL) has been established for B12, due to its low level of toxicity. UL refers to the maximum daily dose of a vitamin unlikely to cause adverse side effects in the general population.
Is oral vitamin B12 therapy effective for B12 deficiency?
Because most clinicians are generally unaware that oral vitamin B12therapy is effective,17the traditional treatment for B12deficiency has been intramuscular injections.
Is lifelong intramuscular vitamin B12 replacement effective in patients with pernicious anemia?
Abstract Many patients with pernicious anemia are treated with lifelong intramuscular (IM) vitamin B12 replacement. As early as the 1950s, there were studies suggesting that oral vitamin B12 replacement may provide adequate absorption.
Is there an effective alternative to vitamin B12 IM injections?
We conclude that oral vitamin B12 is an effective alternative to vitamin B12 IM injections. Patients should be offered this alternative after an informed discussion on the advantages and disadvantages of both treatment options. Keywords: oral vitamin B12, pernicious anemia, mecobalamin, cobalamin, cyanocobalamin Introduction
Is oral vitamin B12 replacement effective in gastric cancer patients?
Intramuscular injection of vitamin B12 is the only known treatment. We investigated the efficacy and safety of oral vitamin B12 replacement for gastric cancer patients with vitamin B12 deficiency after total gastrectomy.